mAb anti-Human NSE, 145

Description

Description: Mouse monoclonal antibody to human Neuron Specific Enolase (NSE)

Purification: Protein G affinity purified

Product Type: Primary antibody

Target Protein: Human NSE

Immunogen: Recombinant  human NSE

Fusion Myeloma: Sp2/0-Ag14

Specificity: This monoclonal antibody reacts with recombinant human NSE.

Species Reacitvity: Human, others not tested

Host / Isotype: Mouse, IgG2b Kappa

Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00mg/mL. 

Storage: Store at -20^oC

Research Area: Neurological study

Background:  

NSE (Neuron-Specific Enolase) is a glycolytic enzyme present in high concentration in neurons and in central and peripheral neuroendocrine cells.   The protein showed specific neurotrophic and neuroprotective effects on cultured neuron cells in low oxygen condition and was found to increase expression after traumatic brain injury.  Serum NSE level has been evaluated as a biomarker for predicting the outcome of patients after brain injury and for identifying brain injury in multiple organ trauma.  Immuno-detection of NSE is used for identifying cells of neural and neuroendocrine lineage.

Application: ELISA, Western Blot  

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.